Prostaglandin E2 (PGE2)
CAS No. 363-24-6
Prostaglandin E2 (PGE2) ( Dinoprostone | Prostaglandin E2 | PGE2 )
产品货号. M19799 CAS No. 363-24-6
前列腺素E2是一种类激素物质,参与多种身体功能,如平滑肌的收缩和舒张、血管的扩张和收缩、血压的控制以及炎症的调节。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥389 | 有现货 |
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| 5MG | ¥551 | 有现货 |
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| 10MG | ¥761 | 有现货 |
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| 25MG | ¥1596 | 有现货 |
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| 50MG | ¥3070 | 有现货 |
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| 100MG | ¥4771 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Prostaglandin E2 (PGE2)
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述前列腺素E2是一种类激素物质,参与多种身体功能,如平滑肌的收缩和舒张、血管的扩张和收缩、血压的控制以及炎症的调节。
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产品描述Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.(In Vitro):Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
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体外实验Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
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体内实验——
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同义词Dinoprostone | Prostaglandin E2 | PGE2
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通路GPCR/G Protein
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靶点Prostaglandin Receptor
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受体EP2?Receptor|Human Endogenous Metabolite
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研究领域Others
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适应症Labour induction
化学信息
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CAS Number363-24-6
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分子量352.47
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分子式C20H32O5
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纯度>98% (HPLC)
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溶解度DMSO:35.3 mg/mL(100 mM)
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SMILESCCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
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化学全称(Z)-7-((1R2R3R)-3-hydroxy-2-((SE)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Fernandez-Repollet E et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70.
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