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Prostaglandin E2 (PGE2)

CAS No. 363-24-6

Prostaglandin E2 (PGE2) ( Dinoprostone | Prostaglandin E2 | PGE2 )

产品货号. M19799 CAS No. 363-24-6

前列腺素E2是一种类激素物质,参与多种身体功能,如平滑肌的收缩和舒张、血管的扩张和收缩、血压的控制以及炎症的调节。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥389 有现货
5MG ¥551 有现货
10MG ¥761 有现货
25MG ¥1596 有现货
50MG ¥3070 有现货
100MG ¥4771 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Prostaglandin E2 (PGE2)
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    前列腺素E2是一种类激素物质,参与多种身体功能,如平滑肌的收缩和舒张、血管的扩张和收缩、血压的控制以及炎症的调节。
  • 产品描述
    Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle the dilation and constriction of blood vessels control of blood pressure and modulation of inflammation.(In Vitro):Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
  • 体外实验
    Prostaglandin E2 (GMP) (10 nM, supplemented in basic culture medium) blocks Paneth cell formation in cultured human small intestinal organoid (hSIO).Prostaglandin E2 (GMP) (1 or 10 μM, 24 h ) increases proliferation of undifferentiated NE-4C stem cells.Prostaglandin E2 (GMP) (1 μM, 8 day) promotes the progression of NE-4C stem cell differentiation into neuronal-lineage cells.Prostaglandin E2 (GMP) (1 μM, 6 or 8 day) increases the expression of Cadherin-2 (neurosphere adhesion marker).Prostaglandin E2 (GMP) (1 μM) enhances hematopoietic stem cells (HSCs) homing, survival, and proliferation.
  • 体内实验
    ——
  • 同义词
    Dinoprostone | Prostaglandin E2 | PGE2
  • 通路
    GPCR/G Protein
  • 靶点
    Prostaglandin Receptor
  • 受体
    EP2?Receptor|Human Endogenous Metabolite
  • 研究领域
    Others
  • 适应症
    Labour induction

化学信息

  • CAS Number
    363-24-6
  • 分子量
    352.47
  • 分子式
    C20H32O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:35.3 mg/mL(100 mM)
  • SMILES
    CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
  • 化学全称
    (Z)-7-((1R2R3R)-3-hydroxy-2-((SE)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Fernandez-Repollet E et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30(5):466-70.
产品手册
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